Scott Rocklage Is Fighting For A Cure

Managing partner of 5AM Venture, Scott Rocklage, announced that the company has joined in a $55.3 million in a Series A round of funding for Expansion Therapeutics. Novartis Venture Fund, Kleiner Perkins, Sanofi Ventures, along with 5AM Venture, were all participants in this round of funding.


Expansion Therapeutics will be using this money to fight the diseases it has in its portfolio. Specifically, they are looking for treatments for myotonic dystrophy type 1. Also known as DM1, myotonic dystrophy type 1 is the leading cause of muscular dystrophy in all adults.


What Is Myotonic Dystrophy

The condition of myotonic dystrophy type 1 occurs when the production of RNAs reach toxic levels in the cells. This is when muscles, the heart, the hormonal system, the gastrointestinal system, the respiratory system, and the central nervous system start to become defective.


In the United States muscular dystrophy affects 1 in every 5,600 to 7,700 males age 5-24. Worldwide that number is 1 in every 8,000.


Currently there is no effective cure for DM1 which is why Rocklage and Expansion Therapeutics’ work is so important.


Expansion Therapeutics’ Approach

Expansion Therapeutics are working on medications that fight the RNA in this type of illness. They focus on illnesses that are expansion repeat disorders. These are illnesses that are hereditary and do not respond to conventional treatments. In the case of DM1, this illness can affect entire families, The disease can be passed down from generation to generation.


More About Scott Rocklage

Scott Rocklage earned a Bachelor of Science degree in chemistry from the University of Berkeley. He then went on to the Massachusetts Institute of Technology where he received his PhD.


With over 30 years of healthcare management experience, Dr. Rocklage bring a wealth of knowledge to 5AM Ventures. He was named managing partner of the firm in 2003. Learn more:

HCR Wealth Advisors Provides Practical Advice for the Sandwich Generation

We have heard of Generation X, the Millennials, and Generation Z. But does anyone know about the Sandwich Generation? This isn’t an age group that is known for its love of baloney or peanut butter sandwiches. Instead, this group is categorized by people who fall between the ages of 30 and 50 years old who have to take care of their aging parents while helping their children go through college. In other words, their income is being “sandwiched” between their family members.


HCR Wealth Management realizes that this group has the extra burden of caring for many people within their family circle. HCR Wealth is registered investment advisory firm that works to educate clients on investment strategy and helps create personalized strategies to help clients reach their financial goals.


One thing that sandwich generation members should do is to safeguard their nest eggs for their golden years. They can accomplish this by taking advantage of their employer’s retirement plan or they can start their own independent retirement plan.


Retirement savings is a must for any person who is a part of the sandwich generation. When a middle age person has to support their children and their parents they can tend to forget about their own needs. This means they might not have the money they need for retirement or to live comfortably.


People that have to take care of their parents should thoroughly evaluate all of their parents’ economic sources. They should make this type of evaluation to ensure that their parents are receiving as much financial support as possible. Having this extra support will help to ease the burden off of their own finances. Remember, if parents have their own income it would be better for them to use it than to rely on their adult children for support.


Sandwich generation members can use HCR Wealth Advisors to reach their financial goals. The advice HCR Wealth provides will be personalized for their client’s personal situation. Sandwich generation members does not have to lose money while caring for the people they love the most. HCR Wealth Management can help them to increase their wealth while sustaining their finances.


HCR Wealth Advisors is not affiliated with this website

Award Winning AvaTrade Review Is Impressive

Who wants to trade Forex with a mundane broker when you could trade with an award-winning brand? How many awards has AvaTrade won? Learn about the award-winning Forex broker in AvaTrade Review.


Ten Years & Counting

AvaTrade has been around for 10 years and counting. It started its business back in 2006, before the capital markets almost collapsed in 2008. It has withstood the test of time.


Is AvaTrade regulated? Yes. It is regulated by the Central Bank of Ireland, ASiC and FSA.


You can make your minimum deposit of 250 in dollars, pounds or euros. Practice trading commodities, fiat currencies, crypto currencies, indices or ETFs using a demo account. AvaTrade even has an Islamic account.


You don’t need to try to learn an arcane Forex trading platform at AvaTrade. It offers the standard MetaTrader 4 (MT4) system. You know that signal providers will work with Meta Trader 4.


There are plenty of digital coins available at AvaTrade, including Bitcoin, Dash and Ripple. This sets AvaTrade apart from the other brokers.


Plug In Functionality

Experts like the fact that you have plenty of plug-in functionality at AvaTrade. You can plug in Mirror Trader, ZuluTrade and RoboX. These automate or mirror trades to give you more consistency and speed. You can modify the API to your exact specifications.


AvaTrade has AAA customer service according to Broker Notes. This is due to the multiple languages supported in live chat, phone or email. You can get a question answered quickly.


Consecutive FX Empire Awards

The consecutive AvaTrade awards from FX Empire from 2013 to 2016 are also a nice feature. These included “Best Broker” awards. The system is easy to use and popular.


All in all, the latest AvaTrade Review found a very simple, straightforward Forex trading platform. It offers some of the most popular assets and an award-winning platform for success. You can make money anytime on AvaTrade.

Ryan Seacrest Talks About His Big Break In Showbiz

With tv shows, radio shows, red carpet events, a line of formal menswear, and a production company Ryan Seacrest is the busiest person in Hollywood. He says he gets up each day at 5:00 a.m. or 5:15 a.m. and by 6:00 a.m. he is on the radio. During his day he makes sure he does work out at some point each day, something he admits wasn’t a priority for a while. He says it is because he is inpatient that he gets so much done each day.

Ryan Seacrest said in an interview that he considers getting to be on the radio when he was 16-years-old. He said he considers this his own personal big break. However, the real break occurred when he was chosen to be on American Idol. The show turned into a cultural institution and propelled his fame internationally. He said he took advantage of this by building his own brand and expanding his businesses. Because of American Idol he was able to get meetings with people who wouldn’t have talked to him before that.

Ryan Seacrest grew up in Atlanta and attended the University of Georgia. He says he had an opportunity to head to California and if he didn’t take it the chance wouldn’t come again. So, he dropped out of school and moved. He said he promised his parents that if he couldn’t support himself within a year he would move back.

He became a host in 1993. His first show was Radical Outdoor Challenge which appeared on ESPN. He soon founds jobs hosting some children’s shows including Wild Animal Games and Click. In 2000 he was chosen to host Saturday Night Movie on NBC. He was also hired to host another show called Ultimate Revenge in 2001 which was a reality tv show.

During the first year of American Idol, Ryan Seacrest had been the co-host with Brian Dunkleman who is a comedian. The next season he was the only host as Dunkleman decided to move on. He has now hosted many shows such as the annual New Year’s Rockin’ Eve.

Learn more about Ryan Seacrest here:

Madison Street Capital – Recap

Madison Street Capital has made its name by serving the invest needs of mid cap corporate America. The Organization is valued at $50-100 million and this is the price range where many corporations are striving for success. There is strict competition to make it to the top and Madison Street Capital prides itself on being the best firm to do the job. They are known industry wide for their integrity, expertise, and experience. The company is headquartered in Chicago, Illinois and they serve some of the top executives in the country and around the world. The city serves as the perfect hub for meeting and greeting their clients and courting them in a professional environment.


Being well versed in the intricacies of corporate finance, Madison Street Capital has made it their sole mission to provide their exclusive clients with the best results possible pertaining to the financial markets. Their track record with obtaining the best results anywhere from heir impressive portfolio of hedge funds, ETFs, stocks, options, and bonds has been the cause of many clients’ wealth. It is intriguing to see how they have been able to achieve these financial victories. They are creative and innovative in their investment approach, that is the prime reason why their clients love and respect them so much. They have expert knowledge in areas like corporate governance, tax, bankruptcy, asset valuation, liquidation, acquisition, and mergers.


They have offices all over the world an serve clients in multiple countries. Madison Street Capital serves Ghana, India, Chicago, and Oregon. Their global approach to business makes them a force to be reckoned with, so when companies are looking for someplace to invest in they are positive they made the right choice. Their tax planning and wealth preservation department serve their clients by allowing certain clientèle the privacy of managing their funds to obtain the most favorable financial position in the eyes of legislative entities. Madison Street Capital has recently announced their software division, DCG Software value. This division is a world leader in software analytics and has recently undergone a merger with Spitfire Group. Their software utilizes the latest technology to address everyday business obstacles. They serve their clients by offering analytic services, big data, and project support.


Read to learn more.

Daniel Taub

Daniel Taub is noted to be an international lawyer and diplomat. He has been the Israeli ambassador to the UK, and joined the Israeli Foreign Ministry in the 1990s. This was his opening into Israeli diplomacy. He also has credentials as an international writer and lecturer. His area of expertise is international law and negotiation theory. Learn more about Daniel Taub:

He also served as speech writer for former Israeli President, Chaim Herzog. Taub has articles published in several news dailies including “The Huffington Post”, “The Guardian”, and “The Telegraph”. He has written extensively about Israel from a religious and political standpoint.

In a November 2013 article published in “The Independent News,” Daniel Taub voiced genuine concern resulting from the Geneva Deal signed between Iran and other nations. He felt this accord failed to address Iran’s military program or nuclear proliferation. Read more: Daniel Taub | LinkedIn and Daniel Taub | Ideamench

Moreover, shortly after the accord was signed it became apparent that in principle, Tehran and the signing nations differed on interpretation of some key terms. Daniel Taub viewed Iran’s interest in achieving long-term stability in the middle east with skepticism as a result of the noted difference in understanding.

In the article, Daniel Taub suggested that the Jewish state may assess its options in how to best deal with the Shia alliance that extends from Tehran to Beirut to as far as the Gaza. He feels a viable option is for Israel to cultivate relations with numerous Sunni nations or gulf states.

Iran and the Shia alliance may share in common the desire to make good on its threat to abolish the Jewish state, if necessary by nuclear means. Israel and the Sunni nations would obviously feel the devastating effect were such a threat realized. Finding areas of mutual cooperation, according to Daniel Taub, are the basis for building relations between Israel and Sunni countries.

Daniel Taub adheres to the diplomatic ideal to work in areas where achievement is possible.

His work as an ambassador involves political dialogue, academic engagement, business and technical cooperation and faith community participation. These areas each require identifying efforts that are possible to realize with others of like mind and diverse opinion.

Securus Technologies Keeping the Threat of Drones at Bay for Prison Facilities

Securus Technologies has finally a found a solution to the issues caused by the illegal and mischievous use of drones to transport contraband items inside the prison. The new drone detection technology by the company would ensure that no drone goes undetected and that the corrections space continues to remain safe and secure. Securus Technologies has promised to develop the technology to its fullest potential further.


If the use of drones is not stopped to supply contraband packages to prison, the inmates will continue to get whatever they want with ease, irrespective of the tight security they have at prisons. In many of the prisons, the inmates are even found to have knives and guns, thanks to the deliveries done through drones. The drones are a highly useful ethnological invention, but the criminals are using it to deliver illegal items inside the prison, and it must stop if the corrections space has to remain safe and secure. The law enforcement and corrections agencies have been trying to find ways to prevent the menace caused due to this new air supply route opened by drones. However, nothing seems to be effective so far.


However, the drone detection technology by Securus Technologies has changed all that. The drone detection technology, even if it is in its primitive stage, has shown quite promise as a full-fledged technology that is capable of stopping the drones from entering the prison space. As soon as the drone enters the perimeter covered by the drone detection technology, the corrections officers would know who would then immediately move to neutralize the drone and seize any contraband item it might have. Such technology would ensure that drones are no longer a threat to the prison. Thanks to Securus Technologies, the drone detection technology would soon be available for all the prisons to install and use.